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Progesterone Cream - Questions answered by Dr John R. Lee, MD and Virginia Hopkins

10/5/2010 

A: Progesterone is a steroid hormone made by the corpus luteum of the ovary at ovulation, and in smaller amounts by the adrenal glands. Progesterone is manufactured in the body from the steroid hormone pregnenolone, and is a precursor to most of the other steroid hormones, including cortisol, androstenedione, the oestrogens and testosterone. 
In a normally cycling female, the corpus luteum produces 20 to 30 mg of progesterone daily during the luteal phase of the menstrual cycle.
A: Progesterone is needed in hormone replacement therapy for menopausal women for many reasons, but one of its most important roles is to balance or oppose the effects of oestrogen. Unopposed oestrogen creates a strong risk for breast cancer and reproductive cancers.
Oestrogen levels drop only 40-60% at menopause, which is just enough to stop the menstrual cycle. But progesterone levels may drop to near zero in some women. Because progesterone is the precursor to so many other steroid hormones, its use can greatly enhance overall hormone balance after menopause. Progesterone also stimulates bone-building and thus helps protect against osteoporosis.
A: Progesterone is preferable to the synthetic progestins such as Provera, because it is natural to the body and has no undesirable side effects when used as directed.
If you have any doubts about how different progesterone is from the progestins, remember that the placenta produces 300-400 mg of progesterone daily during the last few months of pregnancy, so we know that such levels are safe for the developing baby. But progestins, even at fractions of this dose, can cause birth defects. The progestins also cause many other side effects, including partial loss of vision, breast cancer in test dogs, an increased risk of strokes, fluid retention, migraine headaches, asthma, cardiac irregularities and depression.
A: Dr Lee has coined the term "oestrogen dominance," to describe what happens when the normal ratio or balance of oestrogen to progesterone is changed by excess oestrogen or inadequate progesterone. Oestrogen is a potent and potentially dangerous hormone when not balanced by adequate progesterone. 
Both women who have suffered from PMS and women who have suffered from menopausal symptoms, will recognize the hallmark symptoms of oestrogen dominance: weight gain, bloating, mood swings, irritability, tender breasts, headaches, fatigue, depression, hypoglycaemia, uterine fibroids, endometriosis, and fibrocystic breasts. Oestrogen dominance is known to cause and/or contribute to cancer of the breast, ovary, endometrium (uterus), and prostate.
 
A: In the ten to fifteen years before menopause, many women regularly have anovulatory cycles in which they make enough oestrogen to create menstruation, but they don't make any progesterone, thus setting the stage for oestrogen dominance. Using progesterone cream during anovulatory months can help prevent the symptoms of PMS. We now know that PMS can occur despite normal progesterone levels when stress is present. Stress increases cortisol production; cortisol blockades (or competes for) progesterone receptors. Additional progesterone is required to overcome this blockade, and stress management is important.

A: The USP progesterone used for hormone replacement comes from plant fats and oils, usually a substance called diosgenin which is extracted from a very specific type of wild yam that grows in Mexico, or from soybeans. In the laboratory diosgenin is chemically synthesized into real human progesterone. The other human steroid hormones, including oestrogen, testosterone, progesterone and the cortisones are also nearly always synthesized from diosgenin. Some companies are trying to sell diosgenin, which they label "wild yam extract" as a medicine or supplement, claiming that the body will then convert it into hormones as needed. While we know this can be done in the laboratory, there is no evidence that this conversion takes place in the human body.

A: Because progesterone is very fat-soluble, it is easily absorbed through the skin. From subcutaneous fat, progesterone is absorbed into capillary blood. Thus absorption is best at all the skin sites where people blush: face, neck, chest, breasts, inner arms and palms of the hands.
A: For premenopausal women the usual dose is 15-24 mg/day for 14 days before expected menses, stopping the day or so before menses. For postmenopausal women, the dose that often works well is 15 mg/day for 25 days of the calendar month.
 
A: Dr. Lee recommends the creams that contain 450-500 mg of progesterone per ounce, which is 1.6% by weight or 3% by volume. This means that about 1ž4 teaspoon daily would provide about 20 mg/day.
A: During the third trimester of pregnancy, the placenta produces about 300 mg of progesterone daily, so we know that a one-time overdose of the cream is virtually impossible. If you used a whole jar at once it might make you sleepy. However, Dr. Lee recommends that women avoid using higher than the recommended dosage to avoid hormone imbalances. More is not better when it comes to hormone balance.
A: Dr. Lee recommends the transdermal cream rather than oral progesterone, because some 80% to 90% of the oral dose is lost through the liver. Thus, at least 200 to 400 mg daily is needed orally to achieve a physiologic dose of 15 to 24 mg daily. Such high doses create undesirable metabolites and unnecessarily overload the liver.
A: For a detailed explanation of women's hormone balance issues, a hormone balance program, as well as detailed descriptions of how to use natural progesterone, the following books by John R. Lee, M.D. are recommended:
What Your Doctor May Not Tell You About Menopause: The Breakthrough Book on Natural Progesterone, (Warner Books, 1996)
What Your Doctor May Not Tell You About Pre menopause: Balance Your Hormones and Life from Thirty to Fifty (Warner Books, 1999)
Dr Lee's monthly newsletter, the John R. Lee, M.D. Medical Letter, is also highly recommended for the latest news and breakthroughs in hormone replacement therapy, as well as practical, how-to information on hormone balance and optimal health. For more information visit www.johnleemd.comonline, call (800) 528-0559, or write to P.O. Box 84900, Phoenix, AZ 85071.
 
Q: Dear Sally, I am 33 this year and fell pregnant end of 2010, but had a miscarriage 3 weeks pregnant. It took another 13 months before I fell pregnant again, this time the pregnancy lasted 5weeks and then I lost the baby. I started spotting 4 weeks into the pregnancy and was placed on Cyclogest pessaries. I noticed that immediately the cramping stopped and the spotting, unfortunately a week later I did indeed miscarry. I am ovulating, since I have tested for it and have seen it on the scans. My period is regular, every 26 days, but I spot for 5 days and then heavy flow for 2 days, thereafter it tampers down for another 3 days. I don’t have any serious cramping while I have my period, or never had endometriosis; my uterus is according to the Gynaecologist perfect – so it doesn’t seem like I should have a problem? However, I have other symptoms like dry vagina and night sweats too, which seems to be symptoms of low progesterone. So basically, I do ovulate but my Luteal Phase seems to be short or my body is not producing enough progesterone to sustain the pregnancy. During my second miscarriage we tested my progesterone levels and at 4weeks pregnant the count was 18 and the Dr said she would have liked it to be 60 or at least 30 (I don’t know what measurements they use). My question is: do you think my problem is a shortage of progesterone or oestrogen dominant? And would Naturone help me?
A: Yes N, you most certainly are suffering from low progesterone levels. May I suggest you go onto Naturone and double the dose from ovulation onwards, and if there is no menses then continue with the double dose until you are in the 4th month of pregnancy. Thereafter it will be your choice to stay on it for the duration of the pregnancy or slowly wean off it. After the 4th month the placenta takes over the production of progesterone and usually this is sufficient. The most common miscarriage these days is the: Luteal Phase abortions that happen in the first few weeks of pregnancy. The good news is that it will also increase your fertility, so hopefully you will fall pregnant soon. Good luck and take care
Q: I am 34 yrs old. I have 3 kids and have had a full hysterectomy just over a year ago. Since then I have developed IBS and am still experiencing menopausal symptoms. I have recently had food intolerance tests in my local health store and results showed high intolerance to soya. The health advisor suggested it could be low progesterone levels. I explained that I am currently on HRT, taking 2mg of oestrogen. She suggested e-mailing you for advice. My symptoms are as follows: HOT FLUSHES, BREAST TENDERNESS, ANXIETY, LOW SELF ESTEEM, MOOD SWINGS, AGITATION, IRRITABILITY, FATIGUE, TEENAGE ACNE, HEADACHES. IBS
I would be very grateful if you would advise me....
A: Your symptoms are definitely showing horrific hormonal imbalance which is now known as “oestrogen dominance” Oestradial , the fertile female oestrogen, levels start to fall at menopause, and fall 40 – 60%, but progesterone levels start falling at pre menopause, and have plummeted to that of a man at menopause,. However, if you have had a hysterectomy at an early age, you are forced straight into pre menopause and menopause within a couple of months because your ovaries start to dysfunction. Once ovulation ceases (pre-menopause), we suffer severe progesterone deficiency. Without ovulation you produce no progesterone which is needed to keep oestrogen levels under control. We therefore need to take progesterone to bring back the balance. It is also the most important steroid hormone, at the top of the d4 steroid pathway, which is a precursor to so many other essential hormones in your body, including oestrogens
Q: My name is N and I have just been recommended Naturone by a friend of my mum's. I'm a 23 year old female that has suffered from anxiety, panic attacks for about 5 years. I have also been symptomatically diagnosed with hyperglycaemia by a naturopath 6 months ago. I find that I get extremely irritable and short tempered around the middle of my cycle and am starting to get very frustrated by diagnoses from many different doctors. My periods aren't especially painful. I was placed on anti-depressants, and took these for a year but took myself off them as I found they just suppressed my problems but did not solve the root of the problem. I'm currently sexually active, with a low libido and on the contraceptive pill Levelen. I was wondering if you thought your product would benefit me and if I should have my progesterone levels tested before I start using Naturone. Also will I need to stop taking the contraceptive pill? If so, would you recommend any other alternatives? Thank you for your time. Your product has greatly improved my mum's friend’s quality of life and I hope that it will do the same for me.
A: Yes NATURONE will help you. Oestrogen dominance suppresses the levels of Serotonin in the brain and this leads to depression. We are all oestrogen dominant at present, due to pollution and the xeno-oestrogens mimicking oestrogen in the body, and secondly because of our high stress levels which drain our reserves of progesterone. You do not need the progesterone levels checked as no test here in RSA is accurate. You should just get onto 2 ml twice a day from day 12 of your cycle. The first month (or two) you may experience some worsening symptoms as you body detoxes the xeno-oestrogens, but it just gets better and better thereafter. Yes you do need to get off the PILL as that is very much part of the problem (another xeno-oestrogen), and I recommend an IUD preferably the copper-T but definitely NOT the Mirena (as this has a synthetic progestin in it) which will make the depression far worse. Please also watch your diet and cut out all junk food, especially sugar, coffee artificial sweeteners (except xylitol and honey), gluten. Eat lots of fresh veggies and fruit I also recommend taking supplements, Vit B and C, Omega 3 as well as a good multi formula. Do not buy cheap products as they are not bio-available and are a waste of money. Also please spend a half hour before 10,30 or after 2.30 sunbathing as we are all very deficient in Vit D (helps depression, etc etc.)
Biphosphonates do not work for osteoporosis!!
Orthopedic surgeons and bone specialists have been seeing an increasing number of unusual fractures among long-term users of bisphosphonate bone-strengthening drugs such as Fosamax, Actonel, Boniva and Reclast.
The latest and largest study suggests that women who've been on bisphosphonates for more than five years have a nearly three times higher risk of these fractures. Since tens of millions of women take bisphosphonates, this suggests thousands of them may suffer devastating atypical fractures every year.
According to NPR:
"... [A] growing number of experts agree ... that the risk of such fractures should discourage premature use of the drugs... [T]he take-home message is: Don't start one of these drugs too early ... [and[ don't stay on one of these drugs longer than necessary."
Sources:
NPR February 28, 2011
The Journal of American Medicine, March 2, 2011;305(8):783-789. ...........
Hi Sally,
Just a short e mail to say hi and hope you are both well. Just before my walk in the vineyard this morning I was flicking through the TV channels and came to this programme 3 talk on Sabc Africa. We don’t get Sabc 1 2 or 3.And they were discussing bones etc. What a load of rubbish and the gynaecologist ended with his words of wisdom that all women need estrogen for their bones and da da da. It again just made me so thankful that you were an answer to my prayers when I was going through that tough time four years ago with the menopause and continual bleeding etc. Thank you Sally for all that you have done for me and given me the knowledge so that I can pass on the TRUTH to many ignorant people. I have found over these last four years that with many of the women I have talked to, the ones who have stuck with the cream and altering their life styles and making good choices and becoming responsible for their own bodies are the ones who are converted and spread the message. So many just tried the cream for a few months, tossed it aside and have gone on with their old life styles. And they are suffering now. A lot simply refuse to believe that the cream can do so much good. I have example after example of "friends" who are battling health issues because not only do they refuse to buy the cream[ bleating its too expensive but go on overseas holidays regularly or change their habits of drinking diet coke etc. One friend is religiously swallowing fosamex and complaining of stomach ailments. and another has crippled fingers but keeps on drinking sodas. I now just refuse that they will steal my joy and we avoid the health topic altogether. But I have had a few wonderful converts. Thanks Sally for letting me be a part of your team I really do appreciate it and I press on because of the few out there who genuinely want my help. Take care and bless you both, Avis
 
I was recently introduced to the cream Naturone by Pam. I was dubious at first as this cream is not inexpensive. I was willing to try it as I am no spring chicken and with menopause around the corner as well, as me being a potential victim for breast cancer; I took the plunge and started using the cream. When I say I am a potential victim for cancer it is because I have relatives on my father and my mother’s side who have had breast cancer. My mom was also a victim, so I have to go for regular check-ups for this reason. I have only experienced tenderness on my left side and after using Naturone for two months this has disappeared. I was also suffering from bleeding piles for quite some time and nothing seemed to help. After using Naturone this condition suddenly cleared up. As I am no medical expert I cannot prove that it was the cream that helped me, but as I was not using anything else I can only put it down to that. My only complaint is that you cannot get this through your medical aid and as this is a natural progesterone it can only be beneficial for you. We live in such an artificial age and good products like Naturone are hard to come by and it can also be heavy on your pocket. I feel we should all be able to benefit from natural products which do more good than harm.
Thank you
Susan.
Thank you for my previous order; I cannot express fully enough the delight and relief of symptoms that this cream has given me. For years I have (unknowingly) suffered from ovarian cysts culminating in one bursting last year resulting in major surgery and removal of my right ovary and fallopian tube. A few months later another appeared on my left ovary - the size of a football! The pain and swelling was extremely debilitating and I was advised by my gynae that another operation was the only option. Not happy with this prospect I wanted to understand and address the source of the problem. This led me to Stella Berg, who pinpointed the cause - hormonal imbalance - and in turn put me onto your Naturone. Within a couple of weeks of using your cream the swelling reduced completely and of course the consequent pain disappeared - I can now walk without discomfort, I'm no longer plagued by intermittent seizures of pain and my energy levels are rising again. Just absolutely marvellous!!
Please send me a repeat order –
P Higgin
Hope you don't mind my asking a few questions. There is a lot of info on natural progesterone to assimilate. I can see how it would be an obvious choice when menopausal due to its many plusses, but what about a woman in my case, I am still in my 30’s?
I have a few, but not many, of the oestrogen dominance symptoms: hair thinning, PMS, skin problems, fatigue (sometimes, but this comes and goes and might just be due to the five-year old who dominates my life :)) and foggy thinking (since having Noah), which I also thought was just 'natural'. But none of the other symptoms.
I may also have nonovulatory cycles, but don't have a clue if this is so or not (I certainly don't exhibit any of the obvious symptoms for thinking this like cysts, but then one cannot always know?). I haven't ever missed a period, but they are irregular (anything from 21 to 38 days, depending, which my genie puts down to hormones but isn't particularly worried about this) and we have taken numerous 'risks' and tried to fall pregnant (though not consistently) enough times for me to wonder if there isn't 'something' the matter?
I don't have cysts or fibroids on my ovaries - have recently had a scan. But my hair thinning does concern me.
Is there any harm in my using the natural progesterone to see if it will help the hair loss? Any what if I do fall pregnant? Isn't there something about not using the cream during the luteal phase of the cycle as this might lead to abortion? Or is it the other way round, that one should only use it during the luteal phase - I may be confused? Would appreciate your feedback.
W
REPLY
Dear W
The average age these days for nonovulatory cycles (START OF PERI MENOPAUSE) is now 33 whereas 50 years ago it was nearly 50. This is all due to the xeno-oestrogens messing up this delicate hormonal balance. So you may well be experiencing some months of no ovulation and therefore NO progesterone. IT IS DURING PERI-MENOPAUSE WHEN women need progesterone more than any other time of their lives. This is because of the high levels of oestrogen still around at that time of life (so the imbalance is greater … remember that progesterone in nature, should always be there to balance the oestrogen. It is the antagonist to oestrogen). The fact that you have some of those symptoms indicate progesterone deficiency, which may mean the start of nonovulatory cycles. Bear in mind that if you have a period, it does not necessarily that you have ovulated. Fuzzy brain is a sure sign of low levels of progesterone (50% of the progesterone receptor sites are in the brain… Which means that the brain NEEDS progesterone!). If you have been playing around with fertility drugs, you most definitely need the protection that progesterone gives against the oestrogen cancers. You may also be suffering some PND which is also just low levels of progesterone.
So yes I would say you definitely need progesterone! 2ml am and pm from day 12 of your cycle.
If you think you may be pregnant, then you MUST take extra progesterone to prevent the luteal phase abortions. It is this lack of balance between the oestrogens and the progesterone that is causing luteal phase abortions, the now most common cause of miscarriage.
 
DEPRESSION CURE
Of all the natural remedies for depression perhaps one of the most effective yet least discussed is natural progesterone. The link between progesterone and depression is primarily through the action of the enzyme monoamine oxidase. Depression is usually divided into two categories. Reactive, if it is the result of a death for example, and endogenous or clinical when it occurs for no external reason. The latter is also referred to as a depressive illness. Depression is on the increase. Figures for the UK show 10% of the population have mental health problems. In America approximately seventeen million people are affected by it.
Research indicates that the causes are many. The majority of these support the linkage between low levels of progesterone and depression. One in four people become depressed because of allergens within food. A low level of cholesterol increases the risk, hypoglycaemia is another cause. Any stressful event, thyroid malfunction, a low level of serotonin and environmental oestrgens are all know to contribute to the problem. But what of its treatment? Aside from progesterone WHICH WILL PUSH UP SEROTONIN LEVELS NATURALLY nutrition is one of the most widely ignored of the various natural remedies for depression. It can play a major role in overcoming the condition, with a success rate of over 80%. Another very important factor is lack of Vitamin D3 which is obtained primarily from exposing skin to sunlight (preferably between 10am and 2pm for 20 – 30 minutes)
Twice as many women as men suffer from it, and more women are affected by seasonal affective disorder (SAD) than men. In the latter case the cause may be either excessive oestrogen or a low level of progesterone, as progesterone levels drop during dull or cloudless days. This is particularly noticeable in higher latitudes during the winter months. Some of the symptoms of SAD are weight gain, cravings, panic attacks, lack of energy and low libido. Progesterone is involved in sugar metabolism and in increasing libido and energy.
Increasingly progesterone is helping women and men to overcome depression. It acts as a natural remedy for depression by inhibiting the action of the enzyme monoamine oxidase (MAO) which oxidises the amines rendering them ineffective. It has none of the adverse side effects that the synthetic MAOI’s (such as Prosac) have. Progesterone's action as one of the most effective natural remedies for depression is its influence in the metabolism of serotonin and dopamine, both known to play a role in depression.
Serotonin, melatonin, dopamine, adrenaline and noradrenaline are known as monoamines. The amino acid tryptophan is the precursor to serotonin and melatonin while phenylalanine and tyrosine are precursors to dopamine, adrenaline and noradrenaline. A derivative of the amino acid methionine, S-adenosylmethionine (SAMe) has anti-depressive properties, but is extremely expensive.
Methionine, together with the co-factors folic acid and vitamin B12 is an effective and affordable combination of natural remedies for depression. SAMe, folic acid and vitamin B12 influence serotonin metabolism. Depressed people have been found to have low levels of these B vitamins: 1,3,6,12 and folic acid, a higher incidence of hypoglycaemia and an excessive excretion of cortisol.
Progesterone and depression are linked through the interaction of the following drugs which cause an imbalance between the monoamines...
beta-blockers
caffeine
contraceptives
corticosteroids
nicotine
...while oestrgens and cortisol affect mood by disturbing tryptophan metalbolism. Progestins are sometimes thought of as natural remedies for depression. This is a grave mistake as they are the synthetic "progesterones" found in HRT and the Pill and are known to lower levels of natural progesterone and serotonin manufactured in the body. Women suffering from PMS are the victims of a lack of progesterone and depression is a common result. They have been found to have low levels of serotonin in their blood. Ten per cent of women get either acute or chronic postnatal depression (PND) after giving birth, the reason being a sudden drop in progesterone levels once the placenta has come away. A few rare cases (0.5%) develop postnatal psychosis. This is a temporary disorder that is also helped by progesterone. There are many mental and physical symptoms associated with depression. The milder problems in women manifest themselves in PMS and menopause, while the severest appears in PND and pre-menstrual and post-natal psychosis. In very rare cases the latter ends in infanticide, murder or self-mutilation.
All the above mentioned natural remedies for depression can alleviate all or any of the following symptoms...
mental - loneliness; feelings of uselessness; endless crying; irrational behaviour; confusion; feelings of unreality; guilt; feelings of worthlessness; anxiety; agitation; panic attacks; agoraphobia; claustrophobia; irritability; aggression; anger; rage; violent mood swings; rejection of the baby; delusions; hallucinations; visions; voices in the head; suicidal thoughts; paranoia; changed personality, manic depression
physical - asthma; bingeing; bloating; epilepsy; exhaustion; dizziness; hunger; insomnia; migraine; muscular weakness; sinusitis; thirst
Progesterone can help prevent and reverse the above symptoms in both sexes and through all age groups. It is particularly helpful for women during puberty, for PMS and menopause symptoms. It is essential to maintain adequate levels. An underactive thyroid can be the cause of depression, so a test is advisable. If this is diagnosed then supplimental progesterone can help increase thyroid metabolism especially if used in conjunction with the nutrient based natural remedies for depression.
The following nutrients are essential on a daily basis...
15 to 60ml Omega 3 flax oil
50mg zinc (extremely important for PND)
100 to 1000mg niacin (vitamin B3)
100 to 200mg vitamin B6
500mg inositol
500mg choline
1000 to 3000mg vitamin C
10 to 20mg manganese
200mcg chromium picolinate
500-1000mg magnesium
400mcg folic acid
300mcg vitamin B12
500mg-6gm of the essential amino acid tryptophan for the manufacture of serotonin
500mg-2gm tyrosine and 400mg DL- phenylalanine for the production of dopamine
500mg methionine
500mg GABA to relax and calm
The following natural remedies for depression can be taken initially, but should be discontinued once the nutrients take affect...
500mg kava-kava (a natural relaxant)
500-1000mg of St John's Wort (an effective natural anti-depressant with very few adverse side effects - unlike the synthetic SSRI’s (selective serotonin reuptake inhibitors). It works in the same way - by curing the symptom not the cause
Ignatia amara (a herb that helps with grief)
Food should be natural and unprocessed and include organic protein and fibre, particularly complex carbohydrates as this leads to increased tryptophan uptake. At least 50-75% of all food consumed should be raw. Keep meals small and frequent. An interesting fact is that after a large meal progesterone levels drop. Increase intake of cold-water fish such as mackerel, tuna, salmon, and herring, avoiding those with high levels of mercury.
Avoid:
  • all forms of oestrgen
  • the Pill (change to another form of contraceptive)
  • HRT
  • Tamoxifen
  • all non organic dairy products and meat, including chicken, as these often contain oestrgenic growth hormones
  • sugar
  • oxidised fats, i.e. margarine, refined oils, saturated fats and fried foods, in particular fried animal protein
  • milk
  • coffee
  • reduce sodium intake, but replaced with Himalayan salts.
  • wheat, as the protein in wheat has been linked to depression
  • all sodas, in particular diet drinks and sweeteners containing aspartame, which blocks the manufacture of serotonin
  • alcohol

SALLY’s COMMENTS 

Attached is an article on depression, hormonal balance and nutrition. I strongly agree that 3 factors are at play in depression

  1. Xeno-oestrogens have made us all "oestrogen Dominant" which effect our Serotonin levels and the result is depression. Get progesterone levels up ... it regulates Serotonin and it is also known as "Nature's Valium". Often just getting people on to this alone is enough to sort the problem out. However there is more...
  2. Vit D3 deficiencies have a huge role to play. We have now for a few decades smothered our skins in sunscreen filtering creams, thus not getting the Vit D3 we should. Our skin makes Vit D3 when exposed to sunlight. This also explains the normal increase in depression (SADS) during UK winters and also the increase in colds and flus during winter months, when our skins are covered with clothes. This is all due to a depressed Immune system (Vit D3 is essential for a good immune function).If you cannot get the sun then DO supplement with a tablet of Vit D3 x 3 per day until feeling better, then reduce to recommended doses.
  3. Nutrition. Junk food has not only caused obesity, but we are all now deficient in a number of essectial Vits and Minerals which all play a role in Depression . The most important being the VIT Bs, especially Vit B3 (Niacin.

The answer is to address all three areas asap .... it may take some time to build up the immune system and levels of Vit D3 and B, but this is definitely the way forward. Good luck in changing your life. You will look back on this period as a "life-changing time" for the better of course.

My mother attended a talk given by you here in Harare and bought me a tub of Naturone. I had had severe PND after my first baby which lasted for 6 months, and she knew I would give anything not to go through the same thing again. This time round, (my baby is now 3 month) I put 1ml Naturone morning and night and have not had depression, in fact have not had so much as one negative thought. It is quite amazing. It is also wonderful to know that there was a reason for the other depression and that I was NOT going mad ! Many thanks for your product, I will be telling all my pregnant friends about this wonderful product. By the way, I am an amazing cow, this time round, and my baby is so good. Could this also be an effect of this product?
Brenda, Harare
MOYRA had a thyroid problem and was suffering from depression. She started the Naturone cream on 5 May. She initially felt nauseous and very tired, but soon started to feel well. Full of energy and not depressed at all anymore, and has lost 5 kg’s in weight (in only 6 weeks!). Before leaving to live in the UK, she gave us her Thyroid print out 14 March PATIENTS RESULTS CORRECT RANGE
F.T.3. 4.0pmd 2.2 – 5.4
Thyroxine 9.9 9.1 – 23.8
T.S.H. 10.28 0.049 – 4.67
30 May F.T.3. 4.1 2.2 – 5.4
Thyroxine 13.5 9.1 – 23.8
T.S.H. 4.14 0.049 – 4.67
Her doctor is very pleased with this result!
 
Q: My doctor says I am have insulin resistance and could develop Diabetes and that my hormones are all over the place. Please advise me.
A: IF you are suffering from Insulin resistance, you probably have PCOD which in turn has totally messed up your hormones. The hormone the medical profession is looking for when they give you a hormonal blood test at around 40, is oestradial, because they think that peri-menopause and menopausal problems are due to oestrogen deficiency. However, oestradiol should be low in menopause (any age now from 34 on). The change has actually come from Progesterone deficiency which arises in peri-menopause once you stop ovulating. Progesterone will balance everything as it should be in your body at the age you are (as Nature intended it be anyway!!!!). Remember this therapy is prompting your body to heal itself, so do NOT expect instant success. We look at 3 months to get the total balance back. If your insulin is up, you MUST cut out all refined carbohydrates and sugar ... junk food! This is slowly killing you. Take charge of your life from now and you will regain optimum health. Supplements I strongly recommend are Omega 3 Fatty acids (salmon oil), a good, wholefood vitamin and mineral supplement (GNLD or Solgar) and an anti-oxidant formula. (You can order these on this site) Follow the Patrick Holford GL Diet. It is the only real healthy diet and address the problem of insulin resistance.
Q: My daughter started throwing epileptic fits after she started puberty. I am convinced these are connected to her hormones?
A: Yes, Epilepsy starting in puberty may well be due to hormonal imbalance. There is certainly a lot of hope for your daughter's epilepsy if it is an oestrogen dominant epilepsy ... i.e. it started as she went into puberty. Progesterone has amazing results with this type of epilepsy. Supplementation with a natural progesterone for these children is vital. If she is stressed her need for progesterone will increase, as the stress hormones that are manufactured from progesterone, deplete her progesterone levels at this time. She must therefore double the dose during stress. She will soon be able to wean herself off her drugs. I must emphasize that for the first month or so she will go through a detox of oestrogen, and until she has done this she should stay on her drugs. The release of this oestrogen that has been lying dormant on the receptor sites will increase the oestrogen dominance for a while. My recommendation is to double the recommended dose for the first 2 weeks at least.
10/4/2010
1 Comment
Q: I have just been to see my Gynae, Dr A Warnich, and when he did my scan internally and was showing me my uterus, I asked him where my fibroids were. He answered that they must have shrunk, because there was only a tiny one there. So I told him that it must be as a result of the Progestrone, and he said my fibroids would have shrunk naturally anyway because of the oestrogen, and that confused the hell out of me.
Thanks BRENDA
A: That really shows how little he knows about fibroids ...... their growth is STIMULATED by oestrogen. Anyway, don't be confused, be joyful... they have gone !!! And WE know how !!!
Q: I would just like to express my sincere gratitude to your team who were at the Ramada Hotel in Belfast last night. I found the talk to be very informative. I purchased the progesterone cream last night, but I am not entirely sure how much to use. I am 33 years old and suffer from severe migraines that occur at least once a week – this has devastating effects on both my work & family life. I was put on the contraceptive pill (Cerazette) about 3 years ago as my periods were very painful and heavy and my migraines were much more severe at this time. I would like to know if I should stop the pill immediately & how much cream should I use? I look forward to your response.
Many Thanks
Karen McLoughlin
A: Dear Karen Thanks for your kind words. Yes, I would stop the contraceptive pill and get onto Naturone immediately (You can take these together if you want to complete your cycle). You should be on 2ml morning and night from day 13 of your cycle, rubbed anywhere on your body including the face. Over the next few months your migraines should be a thing of the past, your periods should be fine too, but do be aware that symptoms of oestrogen dominance can occur as you go through the detox phase (first month or two)
Take care
 
Q: I have tried coming off HRT before but have suffered serious withdrawal symptoms, so have gone straight back onto it. I know I need to get off this drug. Please help!
A: Always come off drugs slowly. Your body has become used to them and you could have withdrawal effects if you come off the HRT too quickly. I suggest you immediately start using Naturone and then wean yourself off HRT over 3 - 6 months, whichever is best for you. Some people can come off fairly quickly without having withdrawal symptoms, others need longer. On a pill, it is easy , as you would miss every other day for the first month, miss 2 days between dose in the second month. miss 3 days in the third month etc. With the patch, you would cut a quarter out of the patch used in the first month. a half off the second month, 3/4 the 3rd month etc. The implant you just never take another one, but may use more Naturone for those months until you feel totally balanced.
Hi Sally
I wrote to you from Botswana last year as I was about to start Naturone. It has helped tremendously migraines are a thing of the past and my periods are not nearly so heavy. It also helped a lot with insomnia. Of late I feel that things are changing again in my body- towards the end of my cycle last month the insomnia went wild again, I got hold of Ingrid and she got hold of Helen and both said to add an extra spoon would be ok for a short while, I did and it really helped. 10 days into my new cycle thing have gone pear shaped again so have added an extra spoon and things are calming down slowly. I am 42 and have had just about all the symptoms you talk about on the website in varying degrees over the years - I find doctors really unhelpful and unwilling to try and understand that I listen to my body and that things have been changing gradually for the last 4 years. They just don't seem to understand this peri-menopause idea! I am unwilling to pursue the sleeping problem with the doctor as prescription sleeping tablets and anti-depressants make the situation worse and I certainly am not prepared to go the HRT rote, I have several friends who have come badly unglued that way. Can I continue to adjust the cream when the peri menopausal symptoms just aren't manageable on 2 spoons and then readjust when it calms down again?
Thanks so much
Martine Watts
I am 58, I started using Naturone nearly 3 months ago, and have not experienced any lessening of my hot flushes, which I was hoping would at least calm down. Should I continue with the product? Or does it just not work for some people? Kind regards
Marianne.
REPLY
Naturone is excellent to get you through the menopause. It balances oestrogen dominance.... and usually works for Hot flushes, BUT the bottom line is, hot flushes are due to changes in oestrogen levels, and at this stage of life, your oestrogen levels are dropping. Although in most case progesterone works for hot flushes because not only is it the antagonist to oestrogen but also manufactures oestrogen too, (amongst many other hormones it is responsible for ) However, if you are stressed, all the progesterone is siphoned into producing adrenalin and cortisol. I am sure you have already noticed, that as you get worried or angry, immediately a hot flush occurs. There are other triggers for hot flushes too, and these are SUGAR, COFFEE and refined carbohydrates and alcohol. My suggestion is to take a products called Stress damage control (Solal) as well as the Naturone (which by the way will be helping to calm you down, sleep better, be less reactive, lose weight and many other benefits during menopause). I also agree that 3 months is still early days to get hormones into balance. So for all the above reasons, I do think you should continue, but make a few dietary changes as well. Lastly, a change in attitude can do wonders ... regard these flushes as "Power surges", after all you are entering the most powerful time of your life !!.
 
I am 33 this year and fell pregnant end of 2010, but had a miscarriage 3 weeks pregnant. It took another 13 months before I fell pregnant again, this time the pregnancy lasted 5weeks and then I lost the baby. I started spotting 4 weeks into the pregnancy and was placed on Cyclogest pessaries. I noticed that immediately the cramping stopped and the spotting, unfortunately a week later I did indeed miscarry. I am ovulating, since I have tested for it and have seen it on the scans. My period is regular, every 26 days, but I spot for 5 days and then heavy flow for 2 days, thereafter it tampers down for another 3 days. I don’t have any serious cramping while I have my period, or never had endometriosis; my uterus is according to the Gynaecologist perfect – so it doesn’t seem like I should have a problem? However, I have other symptoms like dry vagina and night sweats too, which seems to be symptoms of low progesterone. So basically, I do ovulate but my Luteal Phase seems to be short or my body is not producing enough progesterone to sustain the pregnancy. During my second miscarriage we tested my progesterone levels and at 4weeks pregnant the count was 18 and the Dr said she would have liked it to be 60 or at least 30 (I don’t know what measurements they use). My question is: do you think my problem is a shortage of progesterone or oestrogen dominant? And would Naturone help me?
REPLY
Yes N, you most certainly are suffering from low progesterone levels. May I suggest you go onto Naturone and double the dose from ovulation onwards, and if there is no menses then continue with the double dose until you are in the 4th month of pregnancy? Thereafter it will be your choice to stay on it for the duration of the pregnancy or slowly wean off it. After the 4th month the placenta takes over the production of progesterone and usually this is sufficient. The most common miscarriage these days is the: Luteal Phase abortions that happen in the first few weeks of pregnancy. The good news is that it will also increase your fertility, so hopefully you will fall pregnant soon. Good luck and take care
Q: I am so sick of being unwell, how do I get myself back on top? I know my hormones are out of balance what with taking the pill all my life and living life in the fast lane … help!
A: Supplementing with Naturone for hormone balance is essential in today’s “sea of oestrogen” environment we live in (a result of all the man-made chemicals). You will do great on this therapy, which by the end of 3 month should have your hormones in balance. Supplementing with Naturone for hormone balance is essential in today’s “sea of oestrogen” environment we live in (a result of all the man-made chemicals). You will do great on this therapy, which by the end of 3 month should have your hormones in balance. That's the hormonal balance, now you should look at the nutritional balance too. An optimum state of Health is all about balance in a holistic sense, nothing works in isolation ... physical, emotional, mental and spiritual. Therefore still on the physical level I would recommend nutritional supplements as well. Your diet should be mostly vegetarian, with the occasional organic meat or chicken (Not beef or pork). Sugar, junk food and coffee should be eliminated from your diet. It is important to get your pH above 7 and you can test your pH with litmus paper weekly; To keep the pH right, snack on raw almonds during the day. The nutrient I find that is most lacking in ALL our modern diets is Omega 3 fatty acids. These are essential for hormonal balance, healthy heart, prevention of cancer, and certainly sore joints. I would start on 3 per day for a while and then you can reduce to one per day. Be careful of the Omega 3 you get however, because a cheap product can contain a lot of toxins (eg fish liver oils). You can take either a good Salmon oil or flax seed oil.
Other essential nutrients you need to be on are:-
a good anti-oxidant ,
extra Vit C (a whole food supplement) and
Cal Mag (make sure this is chelated).
A good multi vit and mineral supplement as well will ensure your body has everything it needs on a daily basis to produce healthy cells.
After all you are as healthy as your cells!